2C-B Guide: 2C-B Dosage, Experience, Benefits, & Effects

The drug’s effects increase and decrease in intensity over the course of a trip, though in large part 2C-B is much more controllable than other hallucinogens like LSD and psilocybin mushrooms. He isn’t the only one; back in the club, it’s so warm that condensation is literally dripping down the walls. He’s also getting closed-eye visualisations (CEVs) – colourful patterns that morph repeatedly – but, beyond the trailing lights, he’d need a bigger dose to experience full-on open-eye visualisations (OEVs). Emax values of vital signs and cortisol were compared with baseline data using a paired samples t-test. Furthermore, a detailed comparison between different time points was performed by means of a one-way repeated measures ANOVA, with time condition as factor.

Psychological Symptoms of 2C-B

In August 2007, 2C-B, along famous fetal alcohol syndrome with many other psychologically active substances,[44] was added to Ley 20.000, known as the Ley de Drogas [es].

What Does 2C-B Feel Like?

Mixing 2CB with other psychedelics like LSD, mescaline, or magic mushrooms can lead to much stronger hallucinations. The more 2C-B you take, the further the experience diverges from MDMA. High doses are very psychedelic and can make being at public events very uncomfortable — unlike MDMA. Both 2C-B and mescaline are thought of as being “gentle” when compared to other psychedelics and the visuals are very similar between the two. 2C-B is more stimulating than mescaline and has much less “headspace.” Headspace refers to the introspective and existential thoughts that accompany the psychedelic experience.

Every milligram of 2C-B can affect the experience and so “eyeballing” a dose of powder could get you in deeper than you bargained for, which once happened to Boreta. When experiencing a bad trip or overdose, seek medical attention immediately. While hallucinogens are not typically addictive, 2C-B’s stimulant effects can lead to addiction, causing long-term negative effects. People may depend on the drug to achieve positive feelings, neglecting aspects of their daily lives to acquire or use it. Because the beginning of the high is painful, most people report having an unpleasant experience with the drug. Behavioral, neurochemical and pharmaco-EEG profiles of the psychedelic drug 4-bromo-2,5-dimethoxyphenethylamine (2C-B) in rats.

Mixing 2C-B with other drugs

1. 2C-B is also likely to interact negatively with other stimulating substances, such as amphetamines (Adderall), MDMA, MDA, cocaine, caffeine, and nicotine.
2. However, it’s more accurate to suggest the effects of 2C-B resemble mescaline — which is actually the molecule used as inspiration for creating the entire 2C class of drugs, to begin with.
3. But because 2C-B is also a stimulant, there may be a potential for abuse that doesn’t exist with LSD and shrooms.
4. Of the survey respondents that too more than 35 mg of 2C-B, nearly 28% of them had a hangover the following morning.

At this time, it’s unclear whether it’s worthwhile to microdose with 2C-B. One mother who took the drug with her son—who had recently moved away—learned how to let go as a parent and accept his individuality. Importantly for their relationship, she came to appreciate him as a separate, self-contained being.[37] Others report its usefulness in strengthening bonds between couples. 2C-B is metabolized by the monoamine oxidases (MAOs) A and B, so it likely poses a risk for people on MAO inhibitors (MAOIs).[19][20] These include some types of antidepressants, as well as ayahuasca.

Some studies even suggest 2C-B may act as an inhibitor of the 5-HT2A receptor [3]. Additionally, the few clinical trials that are available involving 2C-B have all reported the drug had little to no side effects and that the drug had a high level of safety. As part of our ongoing experience surveys, we ask our readers to share their experiences to better understand the effects and common dosages of substances. Because there’s so many anecdotal reports that 2C-B has relatively few negative side effects, there’s some speculation that it could be a reasonable choice (or alternative to MDMA) in psychedelic-assisted therapy. And although it was used by some therapists before it was outlawed in the mid-Nineties, the research into its safety and application is scant.

And like all psychedelics, those with certain mental health conditions, like schizophrenia or bipolar disorder, also need to be extra careful because of the increased risk of inducing a psychotic or manic reaction. Results were similar to those described in previous works and surveys, all symptoms were resolved by 6 h (Caudevilla-Gálligo et al., 2012; Nugteren-van Lonkhuyzen et al., 2015). It seems so for healthy individuals, and there have been no deaths linked to its use.

Subsequently, the statistical analysis presented was performed without considering these factors. Subjective effects of 2C-B were measured using a set of the visual analog scale (VAS), the Addiction Research Center Inventory (ARCI), the Evaluation of the Subjective Effects of Substances with Abuse Potential (VESSPA-SSE) questionnaires, and the HRS. Visit the following websites to learn about The Recovery Village’s network of rehabilitation facilities. Each center is ready to help people learn how to cope with their addiction and uncover the root causes for their substance use disorder. To our best knowledge, there have been no scientific studies into the long-term effects of 2C-B use.

If you want to contribute your experience to improve our understanding of 2C-B or other psychedelics, consider filling out one or more of our psychedelic surveys and sharing your experience. It is important to note there have been deaths linked to other substances in the 2C family (like 2C-T-7 and 2C-I-NBOMe), and one woman suffered brain injury after ingesting an unknown dose of possibly impure 2C-B. What’s more, some reddit users reported experiencing HPPD after high dose experiences, and two of my 31 survey respondents reported seeing some trails in substance use group activities the weeks following their 2C-B trip, although they eventually faded.

2C-series, also called 2C-drugs/compounds, are a related group of substances with presumably psychedelic and psychostimulant properties. All of them are phenylethylamine derivatives structurally close to mescaline with methoxy substitutions at the 2 and 5 positions derived from the two carbon molecules between the benzene ring and the amino group. 2,5-dimethoxy-4-bromophenethylamine (2C-B, Nexus) is one of the oldest and best known 2C-type eco sober house drugs.

-B Effects: What’s a 2C-B Trip Like?

Further experimental research under controlled conditions is needed to compare human pharmacology of 2C-B with other classical drugs. 2C-B produced robust changes in most subjective effects measured by VAS, ARCI, and VESSPA-SEE. Table 2 shows the results for the different subscales of the questionnaires. If your use of 2C-B is affecting your health, family, relationships, work, school, financial or other life situations, or you’re concerned about a loved one, you can find help and support.

Studies show that most people who use these drugs are young adults who frequently attend raves. Most people take 2C-B orally and experience a burning sensation when ingesting the drug. Occasionally, people snort it, though doing so often causes nosebleeds and is potentially lethal.

“CEV [closed eye visuals] were very reminiscent to LSD in a playful, whimsical manner with an emphasis on pink and green colors. [They were] complex and symbolic with depth and layering,” said Adrian. Because 2C-B is illegal and produced in secret laboratories, these illicit drugs are often laced with other substances, causing significant physical and mental risks. In addition, the amount in a single capsule or tablet can vary significantly. Other effects include feeling extremely sociable, though it may be difficult to converse with another person.

Globally, subjects under 2C-B effects reported euphoria, activation and a psychedelic experience consisting of a temporary altered state of consciousness. In relation to the MBG subscale, considered a measure of drug-induced euphoria, 2C-B induced high scores which, when regarding to psychedelics, are indicative of subjective feelings of well-being and confidence. As previously postulated for other psychedelics, it is possible that euphoria may also be an essential component of the psychedelic experience after 2C-B use (Bouso et al., 2016). Interesting, 2C-B also resulted in increases in the LSD subscale and somatic VAS scales (drowsiness, dizziness, confusion).